Growth hormone-releasing peptide-6 is the first synthetic hexapeptide studied in animal test subjects and a met-enkephalin derivative that contains a chain of 6 unnatural D amino acids with the sequence (His-D-Trp-Ala-Trp-D-Phe-Lys-NH2).

At Loti Labs, we pride ourselves on stocking high-quality research chemicals. Buy GHRP-6 for sale only for research purposes and not for human consumption. It is available in lyophilized powder form in 5 mg vials.

WHAT IS GHRP-6

Growth hormone-releasing peptide-6 belongs to the family of the Human Growth Hormone secretagogue.

It binds to specific receptors present at the pituitary or hypothalamic level. Studies showed that GHRP-6 receptors are also present in peripheral tissues such as the heart, adrenal, ovary, testis, lung, and skeletal muscle.

STRUCTURE OF GHRP-6

Molecular Formula: C₄₆H₅₆N₁₂O₆

Molecular weight: 873 g/mol

CAS number: 87616-84-0

IUPAC name: (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[2-[[2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoylamino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide

MECHANISM OF ACTION

Studies in animal test subjects show that GHRP-6 stimulates ghrelin which increases the production of growth hormone (GH) by acting at the level of the pituitary or hypothalamus through a specific receptor different from that of the endogenous Growth Hormone-Releasing Hormone (GHRH).

The four important parts of the test subjects that demonstrate the role of GHRP-6 include the pituitary gland, central nervous system, liver, and stomach.

GHRP-6 EFFECTS

The theoretical benefits of GHRP-2 on animal test subjects show that it:

• Increases weight loss
• Increases lean muscle growth,
• Offers cardioprotection
• Improves recovery from injuries

GHRP-6 SIDE EFFECTS

Some of its theoretical side effects are:

• Increased appetite
• Nausea
• Headaches
• Dizziness
• Joint pain
• Fatigue
• Insomnia
• Increased blood pressure

LOOKING FOR WHERE TO BUY GHRP-6 ONLINE

When searching for research peptides online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research. 

Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy GHRP-6 for sale. 

Visit our website or contact us today to buy GHRP-6 online.

References:

1. Argente J, García-Segura LM, Pozo J, Chowen JA. Growth hormone-releasing peptides: clinical and basic aspects. Horm Res. 1996;46(4-5):155–159. doi:10.1159/000185015

2. Ghigo E, Arvat E, Muccioli G, Camanni F. Growth hormone-releasing peptides. Eur J Endocrinol. 1997;136(5):445–460. doi:10.1530/eje.0.1360445

3. Wu D, Chen C, Zhang J, Bowers CY, Clarke IJ. The effects of GH-releasing peptide-6 (GHRP-6) and GHRP-2 on intracellular adenosine 3′,5′-monophosphate (cAMP) levels and GH secretion in ovine and rat somatotrophs. J Endocrinol. 1996;148(2):197–205. doi:10.1677/joe.0.1480197

4. Cheng J, Wu TJ, Butler B, Cheng K. Growth hormone-releasing peptides: a comparison of the growth hormone-releasing activities of GHRP-2 and GHRP-6 in rat primary pituitary cells. Life Sci. 1997;60(16):1385–1392. doi:10.1016/s0024-3205(96)00655-8

1. Frieboes RM, Murck H, Antonijevic IA, Steiger A. Effects of growth hormone-releasing peptide-6 on the nocturnal secretion of GH, ACTH, and cortisol and on the sleep EEG in man: role of routes of administration. J Neuroendocrinol. 1999 Jun;11(6):473-8. doi: 10.1046/j.1365-2826.1999.00364.x. PMID: 10336729.