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LOOKING FOR WHERE TO BUY RAD-140 ONLINE | LotiLabs

LOOKING FOR WHERE TO BUY RAD-140 ONLINE

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LOOKING FOR WHERE TO BUY RAD-140 ONLINE

RAD-140, one of the novel selective androgen receptor modulators (SARMs), has potent anabolic effects on bones and muscles with little androgenic effect.

RAD-140 is particularly interesting to researchers because it is selective about where it works. It targets muscles and bones and has minimal effects on the prostate and other organs.

Buy RAD-140 from Loti Labs, your trusted source for research liquids. It is sold in liquid form in 10mg per ml vials for research only and not human consumption.

Buy RAD-140

WHAT IS RAD-140

RAD-140 is a non-steroidal SARM that binds to androgen receptors with high affinity and specificity and activates AR in breast cancer but not prostate cancer cells.

Because of the high tissue selectivity of their anabolic actions, SARMs are studied in several clinical applications, including sarcopenia, cancer-related cachexia, prostate cancer, breast cancer, and osteoporosis.

STRUCTURE OF RAD-140

IUPAC Name: 2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile

Molecular Formula: C20H16CIN5O2

Molecular weight: 393.8 g/mol

CAS number: 1182367-47-0

MECHANISM OF ACTION

RAD-140 promotes anabolic effects on bones and muscles through binding to androgen receptors, similar to traditional anabolic-androgenic steroids such as testosterone.

In the prostate and breasts, RAD140 acts as an antagonist and blocks AR activation and AR-mediated cellular proliferation. Compared to anabolic agents, SARMs have reduced androgenic properties.

RAD-140 EFFECTS

Some researchers believe that RAD-140 could potentially treat hormone-related or muscle-wasting disorders. Other benefits include:

  • Improve bone formation
  • Improves muscle mass and strength
  • May inhibit both the growth of the prostate in males rats
  • May inhibit androgen receptor-dependent breast cancer
  • Burns fat
  • Boosts testosterone

RAD-140 SIDE EFFECTS

Side effects of RAD-140 include:

  • Hormonal disorder
  • Nausea
  • Headaches
  • Increased Aggression
  • Acne
  • Hair loss

LOOKING FOR WHERE TO BUY RAD-140 ONLINE

When searching for research liquids online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research. 

Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy RAD-140 for sale. 

Visit our website or contact us today to buy RAD-140 online.

References:

  1. LoRusso P, Hamilton E, Ma C, Vidula N, Bagley RG, Troy S, Annett M, Yu Z, Conlan MG, Weise A. A First-in-Human Phase 1 Study of a Novel Selective Androgen Receptor Modulator (SARM), RAD140, in ER+/HER2- Metastatic Breast Cancer. Clin Breast Cancer. 2022 Jan;22(1):67-77. doi: 10.1016/j.clbc.2021.08.003. Epub 2021 Aug 20. PMID: 34565686.
  1. Leung K, Yaramada P, Goyal P, Cai CX, Thung I, Hammami MB. RAD-140 Drug-Induced Liver Injury. Ochsner J. 2022 Winter;22(4):361-365. doi: 10.31486/toj.22.0005. PMID: 36561105; PMCID: PMC9753945.
  1. Barbara M, Dhingra S, Mindikoglu AL. Drug-Induced Liver Injury Associated With Alpha Bolic (RAD-140) and Alpha Elite (RAD-140 and LGD-4033). ACG Case Rep J. 2020 Jun 18;7(6):e00409. doi: 10.14309/crj.0000000000000409. PMID: 33062783; PMCID: PMC7535764.
  1. Yu Z, He S, Wang D, Patel HK, Miller CP, Brown JL, et al. (December 2017). “Selective Androgen Receptor Modulator RAD140 Inhibits the Growth of Androgen/Estrogen Receptor-Positive Breast Cancer Models with a Distinct Mechanism of Action”. Clinical Cancer Research. 23 (24): 7608–7620. doi:10.1158/1078-0432.CCR-17-0670. PMID 28974548

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