Ketotifen Fumarate Liquid Review | Buy Ketotifen Fumarate 1mg per ml (30ml)
17February 17, 2023
Ketotifen Fumarate Liquid Review | Buy Ketotifen Fumarate 1mg per ml (30ml)
Ketotifen Fumarate is a histamine H1 receptor blocker and mast cell stabilizer used to treat mild atopic asthma and allergic conjunctivitis. Ketotifen is also available in capsule form for managing conditions such as asthma and eczema.
Buy ketotifen from Loti Labs, your trusted source for research liquids. It is sold in liquid form in 1 mg per ml vials and is intended as a research chemical, not for human consumption. In the U.S., oral forms of ketotifen are not commercially available and must be sourced from a compounding pharmacy.
Ketotifen Fumarate Review: Purchase 1mg/ml Liquids (30ml)
Ketotifen is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer.
Ketotifen also has pronounced antihistaminic and anti-anaphylactic properties resulting in moderate to marked symptom improvement in most animal models with atopic dermatitis, seasonal or perennial rhinitis, allergic conjunctivitis, chronic or acute urticaria, or food allergy. It is effective in managing symptoms resulting from allergic reactions, such as itching and eye irritation. It is important to consult a healthcare provider before combining ketotifen with other medications to avoid potential drug interactions.
The dosage of ketotifen may be tailored to the individual’s specific medical condition and response to treatment.
STRUCTURE OF KETOTIFEN: A MAST CELL STABILIZER
Molecular Formula: C19H19NOS
Molecular weight: 309.4 g/mol
CAS number: 34580-13-7
IUPAC name: 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one
Ketotifen Fumarate Review: Buy 1mg/ml (30ml) Research Liquid
Ketotifen is a non-competitive histamine antagonist and mast cell stabilizer. Ketotifen is absorbed rapidly but undergoes a first pass effect in the liver, which significantly affects its pharmacological activity. During research with rats, ketotifen acted as a non-bronchodilator antiasthmatic drug by inhibiting the effects of endogenous substances known to be inflammatory mediators after oral administration.
Even though effects can take 6 to 12 weeks to become noticed, using ketotifen has been demonstrated to reduce the frequency, severity, and duration of asthma symptoms and may reduce the use of other asthma therapies. Ketotifen is an old drug that has been re-evaluated in clinical studies for its effectiveness in treating chronic urticaria and other allergic conditions.
Ketotifen Fumarate Effects on Allergic Reactions
Ketotifen’s benefits include ameliorating the symptoms of allergic disorders. Which include:
Asthma
Allergic rhinitis
Allergic conjunctivitis
Atopic dermatitis
Chronic urticaria
Cold-induced urticaria
Cholinergic urticaria
Exercise-induced urticaria
Allergic and nonallergic anaphylaxis
Angioedema
Ketotifen Fumarate Adverse Effects
The adverse effects of ketotifen include sedation, dizziness, and dry mouth. Dry mouth is usually a temporary effect that resolves on its own.
The side effects of ketotifen include:
Sedation
Confusion
Disorientation
Tachycardia
Hypotension
Convulsions
Hyperexcitability
Reversible coma
Weight gain
Monitoring liver enzyme levels is necessary when beginning treatment with ketotifen.
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Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy ketotifen for sale.
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References:
Mita H, Shida T: Comparison of anti-allergic activities of the histamine H1 receptor antagonists epinastine, ketotifen and oxatomide in human leukocytes. Arzneimittelforschung. 1995 Jan;45(1):36-40. [Article]
Okabe S, Nakaji S, Tachibana M: Effect of ketotifen on acute gastric lesions and gastric secretion in rats. Jpn J Pharmacol. 1992 Jun;59(2):251-4. [Article]
Hashimoto T, Ohata H, Honda K: Lysophosphatidic acid (LPA) induces plasma exudation and histamine release in mice via LPA receptors. J Pharmacol Sci. 2006 Jan;100(1):82-7. Epub 2006 Jan 11. [Article]
Ito K, Sakamoto T, Hayashi Y, Morishita M, Shibata E, Sakai K, Takeuchi Y, Torii S: Role of tachykinin and bradykinin receptors and mast cells in gaseous formaldehyde-induced airway microvascular leakage in rats. Eur J Pharmacol. 1996 Jul 4;307(3):291-8. [Article]
Yokoyama H, Iinuma K, Yanai K, Watanabe T, Sakurai E, Onodera K: Proconvulsant effect of ketotifen, a histamine H1 antagonist, confirmed by the use of d-chlorpheniramine with monitoring electroencephalography. Methods Find Exp Clin Pharmacol. 1993 Apr;15(3):183-8. [Article]
