IGF-1 LR3 is a synthetic analog of IGF-1 that acts similarly to insulin’s ability to regulate growth hormone (GH) levels. It may be more potent when administered in comparison to normal IGF-1

IGF-1 LR3 is available in lyophilized powder form and sold in 1 mg vials.

At Loti Labs, we pride ourselves on stocking high-quality research chemicals. Buy IGF-1 LR3 for sale for research purposes only and not for human consumption.

WHAT IS IGF-1 LR3?

IGF-1 LR3 is a synthetic peptide and lengthened analog of human insulin-like growth factor 1 (IGF-1). It differs from IGF-1 because it possesses arginine instead of glutamic acid in its third position in its amino acid sequence (arginine 3). It also has 13 more amino acids in its N-terminus, equal to 83 (relative to the 70 of IGF-1).

The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has a very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.

STRUCTURE OF IGF-1 LR3

Molecular formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉

Molecular weight: 9117.5 g/mol

CAS number: 946870-92-4

MECHANISM OF ACTION

Available research using IGF-1 LR3 on animals found that the peptide binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles.

IGF-1 LR3 obstructs the movement of glucose into the cells of the body of research animals, facilitating fat burning and the use of fat in the body for energy production.

IGF-1 LR3 is approximately three times more potent than IGF-1 and possesses a significantly longer half-life of about 20–30 hours.

IGF-1 LR3 EFFECTS

Studies on rats showed many beneficial effects of IGF-LR3, including:

• Increased cellular repair 
• Anti-aging effects
• Promoting muscle growth, strength, and performance
• Increased bone mineral content
• Improved cognitive functions, improves learning and memory
• Regeneration of the nervous system and brain health
• May reduce the risk of heart & cardiovascular diseases
• Strengthened immune system
• Anti-inflammatory effects
• Improved gut health

IGF-1 LR3 SIDE EFFECTS

Some possible side effects of IGF-1 LR3 may include the following:

• Possible correlation insulin-like growth factor 1 to certain forms of cancer development
• Low blood sugar
• Joint pain
• Nausea
• Acne

LOOKING FOR WHERE TO BUY IGF-1 LR3 ONLINE

When searching for research liquids online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research. 

Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy IGF-1 LR3 for sale. 

Visit our website or contact us today to buy IGF-1 LR3 online.

References:

1. Von der Thüsen JH, Borensztajn KS, Moimas S, van Heiningen S, Teeling P, van Berkel TJ, Biessen EA (2011). “IGF-1 has plaque-stabilizing effects in atherosclerosis by altering vascular smooth muscle cell phenotype”. Am. J. Pathol. 178 (2): 924–34. doi:10.1016/j.ajpath.2010.10.007. PMC 3069834. PMID 21281823.

2. Mohan S, Baylink DJ (2002). “IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms”. J. Endocrinol. 175 (1): 19–31. doi:10.1677/joe.0.1750019. PMID 12379487.

1. Tomas FM, Knowles SE, Owens PC, Chandler CS, Francis GL, Read LC, Ballard FJ (1992). “Insulin-like growth factor-I (IGF-I) and especially IGF-I variants are anabolic in dexamethasone-treated rats”. Biochem. J. 282 ( Pt 1): 91–7. doi:10.1042/bj2820091. PMC 1130894. PMID 1371669.