GHRP-2 GROWTH HORMONE RELEASING PEPTIDE
07September 7, 2022
GHRP-2 GROWTH HORMONE RELEASING PEPTIDE
Growth Hormone Releasing Peptide-2 (GHRP-2) is a potent member of the Growth Hormone Releasing Peptide family, closely related to GHRP-6, a hexapeptide of an earlier generation.
We recognize that a vast amount of study has been carried out on the functionality of GHRP-2 and would like to state once again that its use is limited to animal test subjects only.
GHRP-2 is available in lyophilized powder form and sold in 5mg vials. The lyophilized growth hormone form enhances shelf life and facilitates handling, making it easier to store and use in research settings.
At Loti Labs, we pride ourselves on stocking high-quality research chemicals. Buy GHRP-2 for sale for research purposes only and not for human consumption.
What You Need to Know About GHRP-2: Definition and Uses
Growth Hormone Releasing Peptide-2, also referred to as Pralmorelin or KP-102, is a new 2nd generation synthetic hexapeptide containing six amino acids, D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide.
GHRP-2 studies in animals show its functionality as a growth hormone secretagogue (GHS). It is a synthetic agonist of the hormone ghrelin, a newly-discovered gut peptide that binds to the growth hormone secretagogue receptor).
Ghrelin has two unique effects, stimulating both GH secretion and appetite initiation.
STRUCTURE OF GHRP-2
Molecular Formula: C45H55N9O6
Molecular weight: 817.9 g/mol
CAS number: 158861-67-7
IUPAC name: (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-aminopropanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
Studies on animal test subjects suggest that GHRP-2 enhances natural growth hormone production in two ways.
First, the GHRP-2 intensifies the natural growth hormone releasing signal, resulting in a substantial gh release.
Second, it suppresses a hormone in the body of test subjects called somatostatin, also known as growth hormone inhibiting hormone (GHIH).
By restricting the activity of somatostatin, GHRP-2 can improve growth hormone creation, resulting in increased natural growth hormone levels. GHRP-2 can also enhance muscle growth by promoting protein synthesis and reducing muscle atrophy.
GHRP-2 also activates ghrelin, a peptide hormone produced in the gastrointestinal system, which has strong effects on growth hormone production and appetite.
Mechanism of Action
GHRP-2 is a synthetic peptide that acts as a potent growth hormone secretagogue, stimulating the release of growth hormone from the pituitary gland. This process begins when GHRP-2 binds to ghrelin receptors, which are specialized receptors that play a crucial role in growth hormone regulation. Upon binding, GHRP-2 activates specific signaling pathways that lead to the secretion of growth hormone. This not only enhances growth hormone levels but also stimulates appetite and food intake, making GHRP-2 a valuable tool for researchers studying the intricate balance of growth hormone and appetite regulation.
Understanding the Effects of GHRP-2: Benefits and Side Effects of a Ghrelin Receptor Agonist
The theoretical benefits of GHRP-2 on animal test subjects show that it:
Increases lipolysis
Increases muscle mass
Enhances growth performance by improving feed efficiency and promoting protein deposition
Speeds up wound healing
Promotes heart health
Decreases inflammation of the liver
Pain relief
Interacts with the opioid receptor to produce antinociceptive effects, influencing pain perception
Improves lung injury
Improves sleep
Increases bone density
Improves immunity
Research Applications of GHRP-2
GHRP-2 has a wide range of research applications, making it a versatile tool in scientific studies. Its primary function as a growth hormone secretagogue allows researchers to explore the regulation of growth hormone and its effects on various physiological processes. Additionally, GHRP-2’s ability to stimulate appetite and increase food intake is particularly useful for studies on metabolism and appetite regulation. Researchers also utilize GHRP-2 in studies focused on muscle growth and recovery, especially in the context of athletic performance and bodybuilding. This peptide’s multifaceted applications make it an invaluable asset in the field of growth hormone research.
GHRP-2 SIDE EFFECTS
Some of its theoretical side effects are:
Water retention
Elevated levels of cortisol and prolactin
A feeling of lethargy and tiredness
Decreased insulin sensitivity
Tingling and numbness
Comparative Analysis: GHRP-2 vs. Other Peptides
When comparing GHRP-2 to other growth hormone releasing peptides, such as GHRP-6 and hexarelin, several key differences emerge. GHRP-2 is generally considered more potent than GHRP-6, with more pronounced effects on appetite and food intake. Hexarelin, on the other hand, has a more rapid onset of action but a shorter duration of effect compared to GHRP-2. Additionally, GHRP-2 is often compared to ghrelin, a natural ghrelin receptor agonist. While ghrelin has a more natural mechanism of action, it is less potent than GHRP-2. These comparisons highlight GHRP-2’s unique mechanism of action and its significant role in the study of growth hormone and appetite regulation.
LOOKING FOR WHERE TO BUY GHRP-2 ONLINE
When searching for research peptides online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research.
Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy GHRP-2 for sale.
Visit our website or contact us today to buy GHRP-2 online.
References:
Argente J, García-Segura LM, Pozo J, Chowen JA. Growth hormone-releasing peptides: clinical and basic aspects. Horm Res. 1996;46(4-5):155–159. doi:10.1159/000185015
Ghigo E, Arvat E, Muccioli G, Camanni F. Growth hormone-releasing peptides. Eur J Endocrinol. 1997;136(5):445–460. doi:10.1530/eje.0.1360445
Peroni CN, Hayashida CY, Nascimento N, et al. Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient little mice. Clinics (Sao Paulo). 2012;67(3):265–272. doi:10.6061/clinics/2012(03)11
Liu C, Huang J, Li H, et al. Ghrelin accelerates wound healing through GHS-R1a-mediated MAPK-NF-κB/GR signaling pathways in combined radiation and burn injury in rats. Sci Rep. 2016;6:27499. Published 2016 Jun 7. doi:10.1038/srep27499
