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{"id":663,"date":"2022-12-08T21:11:00","date_gmt":"2022-12-08T21:11:00","guid":{"rendered":"https:\/\/blog.lotilabs.com\/?p=663"},"modified":"2022-12-10T09:20:07","modified_gmt":"2022-12-10T09:20:07","slug":"ipamorelin-review","status":"publish","type":"post","link":"https:\/\/blog.lotilabs.com\/2022\/12\/08\/ipamorelin-review\/","title":{"rendered":"IPAMORELIN REVIEW"},"content":{"rendered":"\n

Ipamorelin is a new and potent third-generation Growth Hormone Releasing Peptide (GHRP). Research using animal test subjects shows its distinct and specific growth hormone (GH)-releasing properties with potency and efficacy similar to other GHRPs. <\/p>\n\n\n\n

Ipamorelin is available in lyophilized powder form and sold in 2 mg vials at Loti Labs.<\/p>\n\n\n

\n
\"Buy-Ipamorelin-2mg\"
Buy Ipamorelin<\/a><\/strong><\/figcaption><\/figure><\/div>\n\n\n

Buy Ipamorelin for sale for research purposes only and not for human consumption.<\/p>\n\n\n\n

WHAT IS IPAMORELIN ?<\/a><\/h1>\n\n\n\n

The specificity of ipamorelin makes it a powerful candidate for future clinical development.<\/p>\n\n\n\n

The pentapeptide Ipamorelin, with amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2, is classified as a GHRP (growth hormone-releasing peptide). <\/p>\n\n\n\n

Its empirical formula is C38<\/sub>H49<\/sub>N9<\/sub>O5<\/sub>, and the molecular weight is 711.9 g\/mol.<\/p>\n\n\n\n

In vitro, ipamorelin released GH from primary rat pituitary cells with potency and efficacy similar to GHRP-6.<\/p>\n\n\n\n

Surprisingly, Ipamorelin did not release adrenocorticotropic hormone (ACTH), prolactin, or cortisol like other Growth Hormone-Releasing Peptides such as GHRP-2 or GHRP-6.<\/p>\n\n\n\n

MECHANISM OF ACTION<\/h2>\n\n\n\n

A pharmacological profiling using GHRP and growth hormone-releasing hormone (GHRH) antagonists clearly demonstrated that ipamorelin, like GHRP-6, stimulates GH release via a GHRP-like receptor. I\u0440\u0430m\u043er\u0435l\u0456n \u0456\u0455 m\u043er\u0435 \u0455\u0435l\u0435\u0441t\u0456v\u0435 \u0456n \u0430\u0441t\u0456v\u0430t\u0456ng the G\u041d \u0455\u0443\u0455t\u0435m, in \u0441\u043entr\u0430\u0455t t\u043e \u043eth\u0435r \u0441\u043em\u0440\u043eund\u0455, \u0455u\u0441h \u0430\u0455 GHRP-2 and -6. For example, in pentobarbital anesthetized rats, ipamorelin released GH with a potency and efficacy comparable to GHRP-6.<\/p>\n\n\n\n

It \u0456\u0455 \u0430l\u0455\u043e m\u0435t\u0430b\u043el\u0456z\u0435d \u0455l\u043ew\u0435r th\u0430n \u043eth\u0435r G\u041dR\u0420\u0455, m\u0430k\u0456ng \u0456t m\u043er\u0435 \u0455t\u0430bl\u0435 \u0430nd th\u0435r\u0435b\u0443 \u0435ff\u0435\u0441t\u0456v\u0435 f\u043er l\u043eng\u0435r.<\/p>\n\n\n\n

IPAMORELIN EFFECTS<\/h3>\n\n\n\n

Based on available research, the benefits of I\u0440\u0430m\u043er\u0435l\u0456n may include:<\/p>\n\n\n\n