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{"id":660,"date":"2022-12-05T20:58:00","date_gmt":"2022-12-05T20:58:00","guid":{"rendered":"https:\/\/blog.lotilabs.com\/?p=660"},"modified":"2022-12-10T09:08:55","modified_gmt":"2022-12-10T09:08:55","slug":"growth-hormone-releasing-peptide-2","status":"publish","type":"post","link":"https:\/\/blog.lotilabs.com\/2022\/12\/05\/growth-hormone-releasing-peptide-2\/","title":{"rendered":"GROWTH HORMONE RELEASING PEPTIDE-2"},"content":{"rendered":"\n

A BRIEF INTRODUCTION OF GHRPs<\/h2>\n\n\n
\n
\"GHRP-2\"
Buy GHRP-2<\/a><\/strong><\/figcaption><\/figure><\/div>\n\n\n

Growth hormone-releasing peptides-2 GHRPs are synthetic, non-natural peptides with potent stimulatory effects on Growth hormone secretion in animal test subjects. They have no structural resemblance with Growth Hormone-Releasing Hormone and act through specific receptors present at the pituitary or hypothalamic level in animals.\u00a0<\/p>\n\n\n\n

The GH-releasing activity of GHRPs is noticeable and dose-related after intravenous subcutaneous intranasal and oral administration.<\/p>\n\n\n\n

Though the way GHRPs work is still a blur, available data postulates that they could act by counteracting somatostatinergic activity both at the pituitary and hypothalamic level and partially through a GHRH-mediated mechanism.<\/p>\n\n\n\n

Recently, GHRP-2 was synthesized and is also available for animal studies. Growth Hormone Releasing Peptide-2 (GHRP-2) is a potent member of the Growth Hormone Releasing Peptide family, closely related to GHRP-6, a hexapeptide of an earlier generation.<\/p>\n\n\n\n

GHRP-2 is available in lyophilized powder form and sold in 5 mg vials.<\/p>\n\n\n\n

At Loti Labs, we pride ourselves on stocking high-quality research chemicals. Buy GHRP-2 for sale for research purposes only and not for human consumption.<\/p>\n\n\n\n

WHAT IS GROWTH HORMONE RELEASING PEPTIDE-2<\/a><\/h1>\n\n\n\n

Growth Hormone Releasing Peptide-2, also referred to as Pralmorelin or KP-102, is a new 2nd generation synthetic hexapeptide containing six amino acids, D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide.<\/p>\n\n\n\n

GHRP-2 studies in animals show its functionality as a growth hormone secretagogue (GHS). It is a synthetic agonist of the hormone ghrelin, a newly-discovered gut peptide that binds to the growth hormone secretagogue receptor). <\/p>\n\n\n\n

Ghrelin has two unique effects, stimulating both GH secretion and appetite initiation.<\/p>\n\n\n\n

MECHANISM OF ACTION<\/h2>\n\n\n\n

The mechanism of action of GHRP-2 on GH release was investigated in experimental animals. <\/p>\n\n\n\n

GHRP-2 was found to stimulate GH release from rat pituitary cells via the same receptor, with a slight variation when compared to GHRP-6. GHRP-2 increases intracellular adenosine 3,5-monophosphate cAMP concentration like that of Growth Releasing Factor (GRF) while GHRP-6 causes a decrease in cAMP levels.<\/p>\n\n\n\n

GROWTH HORMONE RELEASING PEPTIDE-2 EFFECTS<\/a><\/h3>\n\n\n\n

The theoretical benefits of GHRP-2 on animal test subjects show that it:<\/p>\n\n\n\n