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{"id":653,"date":"2022-11-10T14:36:43","date_gmt":"2022-11-10T14:36:43","guid":{"rendered":"https:\/\/blog.lotilabs.com\/?p=653"},"modified":"2022-11-10T14:36:46","modified_gmt":"2022-11-10T14:36:46","slug":"what-is-igf-1-lr3-and-review","status":"publish","type":"post","link":"https:\/\/blog.lotilabs.com\/2022\/11\/10\/what-is-igf-1-lr3-and-review\/","title":{"rendered":"WHAT IS IGF-1 LR3 and Review"},"content":{"rendered":"\n

IGF-1 LR3, also known as Long arginine 3-IGF-1, is a synthetic peptide that acts similarly to insulin’s ability to regulate growth hormone (GH) levels in research animals. <\/p>\n\n\n\n

IGF-1 LR3 is available in lyophilized powder form and sold in 1 mg vials.<\/p>\n\n\n\n

At Loti Labs, we pride ourselves on stocking high-quality research chemicals. Buy IGF-1 LR3 for sale for research purposes only and not for human consumption.<\/p>\n\n\n\n

WHAT IS IGF-1 LR3?<\/a><\/h1>\n\n\n\n

IGF-1 LR3 is a synthetic peptide and lengthened analog of human insulin-like growth factor 1 (IGF-1). It differs from IGF-1 because it possesses arginine instead of glutamic acid in its third position in its amino acid sequence (arginine 3). It also has 13 more amino acids in its N-terminus, equal to 83 (relative to the 70 of IGF-1).<\/p>\n\n\n\n

The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has a very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.<\/p>\n\n\n\n

STRUCTURE OF IGF-1 LR3<\/h2>\n\n\n\n
\"\"\/<\/figure>\n\n\n\n

Molecular formula: C400<\/sub>H625<\/sub>N111<\/sub>O115<\/sub>S9<\/sub><\/p>\n\n\n\n

Molecular weight: 9117.5 g\/mol<\/p>\n\n\n\n

CAS number: 946870-92-4<\/p>\n\n\n\n

MECHANISM OF ACTION<\/h2>\n\n\n\n

Available research using IGF-1 LR3 on animals found that the peptide binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles.<\/p>\n\n\n\n

IGF-1 LR3 obstructs the movement of glucose into the cells of the body of research animals, facilitating fat burning and the use of fat in the body for energy production.<\/p>\n\n\n\n

IGF-1 LR3 is approximately three times more potent than IGF-1 and possesses a significantly longer half-life of about 20\u201330 hours (relative to IGF-1’s half-life of about 12\u201315 hours).<\/p>\n\n\n\n

IGF-1 LR3 EFFECTS<\/h1>\n\n\n\n

When studies on rats were conducted, researchers observed many beneficial effects of IGF-LR3, including:<\/p>\n\n\n\n