Ipamorelin is a pentapeptide and a ghrelin mimetic with growth hormone (GH) releasing activity. It is similar to GHRP-2, GHRP-6, and Hexarelin in stimulating growth hormone (GH) in animal test subjects.

At Loti Labs, we pride ourselves on stocking high-quality research chemicals. Buy ipamorelin for sale only for research purposes and not for human consumption. It is available in lyophilized powder form and sold in 2 mg vials.

WHAT IS IPAMORELIN

Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. 

Besides its presence in the brain, GHSR can also be found in the gastrointestinal tract, heart, lung, liver, kidney, pancreas, adipose tissue and immune cells. 

Unlike other GH releasing peptides, ipamorelin only stimulates GH release in a manner very similar to that of growth hormone releasing hormone.

STRUCTURE OF IPAMORELIN

Molecular Formula: C₃₈H₄₉N₉O₅

Molecular weight: 711.9 g/mol

CAS number: 170851-70-4

IUPAC name: (2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide

MECHANISM OF ACTION

Іраmоrеlіn bіnds tо thе growth hormone releasing peptide reсерtоrѕ, аnd асtіvаtes growth hormone relеаѕе.

It іѕ аlѕо mеtаbоlіzеd ѕlоwеr thаn оthеr GНRРѕ, mаkіng іt mоrе ѕtаblе аnd thеrеbу еffесtіvе fоr lоngеr.

IPAMORELIN EFFECTS

Based on available research, the benefits of Iраmоrеlіn may include:

• Reduced blood pressure
• Reduced stress and anxiety
• Anti-aging effects
• Weight loss
• Increased lean muscle mass

IPAMORELIN SIDE EFFECTS

Below are what researchers noticed during clinical trials with Ipamorelin’s use in animal test studies.

• Headache
• Nausea
• Numbness
• Fatigue
• Decreasing insulin sensitivity
• Water retention

LOOKING FOR WHERE TO BUY IPAMORELIN ONLINE

When searching for research peptides online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research. 

Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy ipamorelin for sale. 

Visit our website or contact us today to buy ipamorelin online.

References:

1. Gobburu JV, Agersø H, Jusko WJ, Ynddal L (September 1999). “Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers”. Pharmaceutical Research. 16 (9): 1412–6. doi:10.1023/A:1018955126402. PMID 10496658. S2CID 12048934.

2. Moulin A, Ryan J, Martinez J, Fehrentz JA (September 2007). “Recent developments in ghrelin receptor ligands”. ChemMedChem. 2 (9): 1242–59. doi:10.1002/cmdc.200700015. PMID 17520591. S2CID 24945528.

3. “Ipamorelin”. AdisInsight. Springer Nature Switzerland AG. Retrieved 10 June 2015.

1. Greenwood-Van Meerveld B, Tyler K, Mohammadi E, Pietra C. Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus. J Exp Pharmacol. 2012 Oct 19;4:149-55. doi: 10.2147/JEP.S35396. PMID: 27186127; PMCID: PMC4863553.