WHAT IS PEG-MGF?
PEG-MGF is Pegylated Mechano Growth Factor. It is a long-acting variant of MGF, a split variant of IGF-1 (but its sequence differs from the systemic IGF-1 produced by the liver). Research has demonstrated that PEG-MGF stimulates myoblasts division and allows muscle fibers to fuse and mature, a process necessary for the growth of adult muscle.
PEG-MGF is available in lyophilized powder form and sold in 2 mg vials at Loti Labs.
Buy PEG-MGF for sale for research purposes only and not for human consumption.
WHAT IS PEG-MGF
PEG-MGF (Pegylated Mechano Growth Factor) is a variant of IGF-1. PEGylation modifies MGF by fusing polyethylene glycol (PEG) into it, increasing its half-life from a few minutes to days.
Subsequently, it is carried through the bloodstream for long periods before being broken down and cleared by the kidneys.
MECHANISM OF ACTION
PEG-MGF modulates muscle inflammation and enhances the regeneration process by improving the recruitment of the white blood cells called macrophages and neutrophils to the injury site, promoting muscle growth and repair.
PEG-MGF also promotes neurogenesis (formation of new nerve cells or neurons) by increasing the number of neural progenitor cells (cells that transform to create specialized cell types).
THE BENEFITS OF PEG-MGF
PEG-MGF proposes to have the following effects on the body of animal test subjects.
The benefits include:
- Strong anabolic effect and ability to repair and rebuild muscles
- Ability to induce muscle hyperplasia (growth of new muscle cells)
- Neuroprotective effect (protects the nervous system and brain functions)
- Mediates myocardial cell survival and myocardium repairs
- Tissue growth and wound healing
- A positive role in bone injury healing
THE SIDE EFFECTS OF PEG-MGF
Side effects associated with PEG-MGF may include the following:
- Hypotension
- Hypoglycemia
- Irregular heart rate
- Swelling of the extremities
LOOKING FOR WHERE TO BUY PEG-MGF ONLINE
When searching for research peptides online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research.
Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy PEG-MGF for sale.
Visit our website or contact us today to buy PEG-MGF online.
References:
- Shang J, Fan X, Liu H. The role of mechano-growth factor E peptide in the regulation of osteosarcoma. Oncology Letters. 2015 Aug;10(2):697-704. DOI: 10.3892/ol.2015.3339.
- Zabłocka B, Goldspink PH, Goldspink G, Górecki DC. Mechano-Growth Factor: an important cog or a loose screw in the repair machinery?. Front Endocrinol (Lausanne). 2012;3:131. Published 2012 Nov 1. doi:10.3389/fendo.2012.00131
- Kravchenko, I.V., Furalyov, V.A. & Popov, V.O. Stimulation of mechano-growth factor expression by myofibrillar proteins in murine myoblasts and myotubes. Mol Cell Biochem 363, 347–355 (2012) doi:10.1007/s11010-011-1187-5
- Matheny RW Jr, Nindl BC, Adamo ML. Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration. Endocrinology. 2010;151(3):865–875. doi:10.1210/en.2009-1217
- Goldspink research on Mechano Growth Factor: it’s potential for optimizing physical training as well as misuse in doping British Journal of Sports Medicine 2005;39:787-788.
