IPAMORELIN REVIEW
Ipamorelin is a new and potent third-generation Growth Hormone Releasing Peptide (GHRP). Research using animal test subjects shows its distinct and specific growth hormone (GH)-releasing properties with potency and efficacy similar to other GHRPs.
Ipamorelin is available in lyophilized powder form and sold in 2 mg vials at Loti Labs.
Buy Ipamorelin for sale for research purposes only and not for human consumption.
WHAT IS IPAMORELIN ?
The specificity of ipamorelin makes it a powerful candidate for future clinical development.
The pentapeptide Ipamorelin, with amino acid sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2, is classified as a GHRP (growth hormone-releasing peptide).
Its empirical formula is C38H49N9O5, and the molecular weight is 711.9 g/mol.
In vitro, ipamorelin released GH from primary rat pituitary cells with potency and efficacy similar to GHRP-6.
Surprisingly, Ipamorelin did not release adrenocorticotropic hormone (ACTH), prolactin, or cortisol like other Growth Hormone-Releasing Peptides such as GHRP-2 or GHRP-6.
MECHANISM OF ACTION
A pharmacological profiling using GHRP and growth hormone-releasing hormone (GHRH) antagonists clearly demonstrated that ipamorelin, like GHRP-6, stimulates GH release via a GHRP-like receptor. Iраmоrеlіn іѕ mоrе ѕеlесtіvе іn асtіvаtіng the GН ѕуѕtеm, in соntrаѕt tо оthеr соmроundѕ, ѕuсh аѕ GHRP-2 and -6. For example, in pentobarbital anesthetized rats, ipamorelin released GH with a potency and efficacy comparable to GHRP-6.
It іѕ аlѕо mеtаbоlіzеd ѕlоwеr thаn оthеr GНRРѕ, mаkіng іt mоrе ѕtаblе аnd thеrеbу еffесtіvе fоr lоngеr.
IPAMORELIN EFFECTS
Based on available research, the benefits of Iраmоrеlіn may include:
- Anti-aging effects
- Faster weight loss
- Increased lean muscle mass growth
- Healthy skin, nails, and hair growth
- Lowering blood pressure
- Less stress and anxiety
IPAMORELIN SIDE EFFECTS
Below are what researchers noticed during clinical trials with Ipamorelin’s use in animal test studies.
- Problems with water retention
- Numbness
- Fatigue
- Decreasing insulin sensitivity
- Headaches
- Nausea
LOOKING FOR WHERE TO BUY IPAMORELIN ONLINE
When searching for research peptides online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research.
Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy ipamorelin for sale.
Visit our website or contact us today to buy ipamorelin online.
References:
- Raun K, Hansen BS, Johansen NL, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552–561. doi:10.1530/eje.0.1390552
- Johansen PB, Nowak J, Skjaerbaek C, et al. Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats. Growth Horm IGF Res. 1999;9(2):106–113. doi:10.1054/ghir.1999.9998
- Andersen NB, Malmlöf K, Johansen PB, Andreassen TT, Ørtoft G, Oxlund H. The growth hormone secretagogue ipamorelin counteracts the glucocorticoid-induced decrease in bone formation of adult rats. Growth Horm IGF Res. 2001;11(5):266–272. doi:10.1054/ghir.2001.0239
- Jiménez-Reina L, Cañete R, De la Torre MJ, Bernal G (2002). “Chronic In Vivo Ipamorelin Treatment Stimulates Body Weight Gain and Growth Hormone (GH) Release In Vitro in Young Female Rats”. European Journal of Anatomy. 6 (1): 37–46. ISSN 1136-4890