Liothyronine is a synthetic form of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium binds to nuclear thyroid receptors. Consequently, liothyronine sodium induces gene expression necessary for growth and development. Liothyronine sodium is more potent than thyroxine (T4). 

According to research, liquid liothyronine sodium may be critical in developing and regulating multiple metabolic processes responsible for homeostasis in animals.

WHAT IS LIOTHYRONINE?

Liothyronine is a synthetic version of the T3 thyroid hormone. Thyroid hormones have necessary functions like controlling metabolism, body temperature, heart rate, and more.

T3 INDICATION FOR USE

In general terms, exogenous liothyronine has shown great potential in replacing insufficient hormonal production and restoring T3 plasma levels in research animals. Other potential uses of liothyronine include:

• Hypothyroidism
• Thyroid cancer (with radiation and surgery)
• Thyroid suppression test

STRUCTURE OF LIOTHYRONINE

Molecular Formula: C₁₅H₁₂I₃NO₄

Molecular weight: 650.97g/mol

CAS number: 15785-49-6

IUPAC name: (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid

MECHANISM OF ACTION

Liothyronine is the most potent form of thyroid hormone. As a salt of triiodothyronine (T3), it is chemically similar and pharmacologically equivalent to T3. As such, it acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body’s sensitivity to catecholamines such as adrenaline.

Liothyronine may also enhance the generation of new neurons in the central nervous system.

Liothyronine has a faster onset of action and a shorter biological half-life than levothyroxine (T4).

LIOTHYRONINE EFFECTS

Based on the studies conducted on animals, liothyronine may play a role in treating the following:

• Symptoms of obesity
• Fibromyalgia, fatigue, and depressive symptoms
• An underactive thyroid, a condition which is also known as hypothyroidism
• Thyroid cancer and goiter
• Infertility due to low thyroid hormone levels
• Myxedema coma

LIOTHYRONINE SIDE EFFECTS

The side effects of Liothyronine seen in animal test subjects include:

• Shakiness
• Fast or irregular heartbeat
• Hair loss
• Fever
• Sweating
• Weight loss
• Weak muscles
• Fatigue
• Anxiety
• Trouble sleeping
• Increased appetite
• Trouble breathing

LOOKING FOR WHERE TO BUY LIOTHYRONINE ONLINE

When searching for research liquids online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research. 

Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy liothyronine for sale. 

Visit our website or contact us today to buy liothyronine online.

References:

1. Mullur R, Liu YY, Brent GA. Thyroid hormone regulation of metabolism. Physiological reviews. 2014;94(2):355-382.

2. Branco M, Ribeiro M, Negrao N, Bianco AC. 3,5,3′-Triiodothyronine actively stimulates UCP in brown fat under minimal sympathetic activity. The American journal of physiology. 1999;276(1 Pt 1): E179-187.

3. Novitzky D, Cooper DK. Thyroid hormone and the stunned myocardium. The journal of endocrinology. 2014;223(1): R1-8.

1. Nagao H, Sasaki M, Imazu T, Takahashi K, Aoki H, Minato K. Effects of triiodothyronine on turnover rate and metabolizing enzymes for thyroxine in thyroidectomized rats. Life sciences. 2014;116(2):74-82.