IGF-1 LR3, also known as Long arginine 3-IGF-1, is a synthetic peptide that acts similarly to insulin’s ability to regulate growth hormone (GH) levels in research animals. 

IGF-1 LR3 is available in lyophilized powder form and sold in 1 mg vials.

At Loti Labs, we pride ourselves on stocking high-quality research chemicals. Buy IGF-1 LR3 for sale for research purposes only and not for human consumption.

WHAT IS IGF-1 LR3?

IGF-1 LR3 is a synthetic peptide and lengthened analog of human insulin-like growth factor 1 (IGF-1). It differs from IGF-1 because it possesses arginine instead of glutamic acid in its third position in its amino acid sequence (arginine 3). It also has 13 more amino acids in its N-terminus, equal to 83 (relative to the 70 of IGF-1).

The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has a very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.

STRUCTURE OF IGF-1 LR3

Molecular formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉

Molecular weight: 9117.5 g/mol

CAS number: 946870-92-4

MECHANISM OF ACTION

Available research using IGF-1 LR3 on animals found that the peptide binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles.

IGF-1 LR3 obstructs the movement of glucose into the cells of the body of research animals, facilitating fat burning and the use of fat in the body for energy production.

IGF-1 LR3 is approximately three times more potent than IGF-1 and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1’s half-life of about 12–15 hours).

IGF-1 LR3 EFFECTS

When studies on rats were conducted, researchers observed many beneficial effects of IGF-LR3, including:

• Reduction of body fat
• Increased metabolism
• Regulation of fat storage and prompts fat to bed used for energy production
• Enhanced physical performance
• Stable muscle growth
• Increased strength
• Prevented age-related atrophy and loss of skeletal muscle function

IGF-1 LR3 SIDE EFFECTS

Some possible side effects of IGF-1 LR3 may include the following:

• Muscle and joint pain
• Nausea
• Headaches
• Hypoglycemia
• Increased risk of developing some cancers

LOOKING FOR WHERE TO BUY IGF-1 LR3 ONLINE

When searching for research liquids online, it is paramount to buy from a trusted laboratory to ensure the integrity of your research. 

Loti Labs offers affordable prices that come with quality control reports. We have in-depth customer support and a generous return policy when you buy IGF-1 LR3 for sale. 

Visit our website or contact us today to buy IGF-1 LR3 online.

References:

1. Tomas FM, Lemmey AB, Read LC, Ballard FJ (1996). “Superior potency of infused IGF-I analogs which bind poorly to IGF-binding proteins is maintained when administered by injection”. J. Endocrinol. 150 (1): 77–84. doi:10.1677/joe.0.1500077. PMID 8708565.

2. Mohan S, Baylink DJ (2002). “IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms”. J. Endocrinol. 175 (1): 19–31. doi:10.1677/joe.0.1750019. PMID 12379487.

1. Tomas FM, Knowles SE, Owens PC, Chandler CS, Francis GL, Read LC, Ballard FJ (1992). “Insulin-like growth factor-I (IGF-I) and especially IGF-I variants are anabolic in dexamethasone-treated rats”. Biochem. J. 282 ( Pt 1): 91–7. doi:10.1042/bj2820091. PMC 1130894. PMID 1371669.