S-4 Sarm Review | Buy Andarine Liquid
S-4 Sarm Review | Buy Andarine Liquid
What is S-4 Andarine, a Selective Androgen Receptor Modulator?
S-4 Andarine, also commercially known as S4, is a type of SARM (Selective Androgen Receptor Modulator). The compound is used for treating muscle wasting issues like osteoporosis and muscular dystrophy in a selective manner, showcasing the therapeutic potential of androgen receptor modulators SARMs.
History of Andarine S4 Andarine S4 was initially developed to treat conditions like muscle wasting and osteoporosis. Additionally, it has been explored for treating benign prostate hyperplasia, with treatment options including 5-alpha reductase inhibitors and anti-androgens.
Research related to S-4 Andarine Research on S-4 Andarine has shown promising results in muscle mass retention and bone density improvement. Clinical trials have been crucial in evaluating the safety and effects of SARMs, highlighting potential side effects and therapeutic uses.
Definition of Andarine S4
Andarine S4 is a type of selective androgen receptor modulator (SARM) that is designed to mimic the effects of anabolic steroids without the negative side effects. It is a fast-acting compound that produces muscle gains within a shorter time frame and is widely used by athletes and bodybuilders due to its potential to transform cutting cycles. As a selective androgen receptor modulator, Andarine S4 specifically targets androgen receptors in muscle and bone tissues, promoting significant improvements in muscle mass and overall body composition.
History of Andarine S4
Andarine S4 was first developed in the early 2000s by a pharmaceutical company called GTX, Inc. It was initially intended for the treatment of muscle wasting diseases and benign prostatic hypertrophy. However, it was later abandoned due to its lack of potency relative to other SARMs. Despite this, Andarine S4 has gained popularity among athletes and bodybuilders due to its ability to promote muscle growth and strength without the negative side effects associated with anabolic steroids. Its unique properties have made it a favored choice for those looking to enhance their physical performance and body composition.
Structure of S-4 Andarine

Molecular Formula: C19H18F3N3O6
Molecular Weight: 441.4 g/mol
Chemical Working Mechanism and Effects on Body Composition
S-4 Andarine is a SARM and is selective in its approach. After ingested by test subjects, its molecules break down and selectively target androgen receptors present in skeletal muscles and bones while leaving out other living cells. Notably, S-4 Andarine does not suppress follicle stimulating hormone (FSH) levels, allowing it to promote muscle and bone mass without the side effects typical of anabolic steroids. Research studies have shown that S-4 Andarine significantly influences the levator ani muscle weight, demonstrating its effectiveness in muscle restoration. When S-4 Andarine binds itself to these receptors, it contributes to a considerable increase in lean muscle mass with little to no side effects. Additionally, it is important to consider the impact of S-4 Andarine on natural testosterone production, as it can suppress testosterone levels, necessitating post-cycle therapy to restore hormonal balance.
Research related to S-4 Andarine
Research has shown that Andarine S4 is effective in promoting muscle growth and strength in both animal models and humans. In a study published in the Journal of Steroid Biochemistry and Molecular Biology, Andarine S4 was shown to increase muscle mass and strength in castrated rats. Another study published in the Journal of Clinical Endocrinology and Metabolism found that Andarine S4 increased lean body mass and decreased body fat in healthy young men. These findings highlight the potential of Andarine S4 to significantly improve muscle mass and reduce body fat, making it a valuable tool for enhancing physical performance and body composition.
Research and Clinical Trials related to S-4 Andarine
S-4 has shown promising results in the trials and research conducted in the past. Post cycle therapy (PCT) is often necessary following the use of S-4 Andarine to restore natural testosterone production and mitigate potential side effects. Animal trials are being conducted to gauge the true efficacy of SARMS and elicit more beneficial effects (and side effects).
S-4 Andarine is known to be highly potent. In a study where metabolites of S1, S4, and S22 were investigated, S4 was shown to have a higher number of metabolites, nine in this case while for S1 it was eight and for S22, and it was four. (Reference 1)
Another study concluded that bioavailability in S-4 is relatively high compared to other SARMs, which means it is readily absorbed by circulatory systems. SARMs also show potential in treating prostate cancer, offering a safer alternative with fewer androgenic side effects compared to traditional anabolic steroids. (Reference 2)
While S-4 has a mild effect on testosterone suppression, it is still advisable to consider PCT to ensure the restoration of natural testosterone levels and to mitigate any potential side effects.
Understanding the Various Uses of S-4 Andarine in Research, Including Muscle Wasting
After ingesting S-4 for a few weeks, research subjects have been shown to be able to increase training hours without feeling exhausted. Furthermore, it helps in releasing testosterone which aids in improving strength and stamina in males. Hormone replacement therapy, particularly in the context of testosterone and SARMs like S-4 Andarine, plays a crucial role in treating conditions such as hypogonadism and managing estrogen levels.
It also aids in weight loss by improving the body’s metabolism. You can intake fewer calories and still build muscle mass with S-4. Research studies have demonstrated that S-4 Andarine positively impacts soleus muscle mass, especially in orchidectomized (ORX) rats, highlighting its anabolic properties in restoring muscle function and mass.
S-4 Andarine has been shown to be effective at low dosages as it is extremely potent.
Comparison to Other Compounds
Andarine S4 is often compared to other SARMs such as Ostarine and Ligandrol. While all three compounds are effective in promoting muscle growth and strength, Andarine S4 is considered to be more potent and faster-acting. However, it also has a higher risk of side effects, particularly vision impairment. This makes it essential for users to carefully consider the benefits and potential risks when choosing Andarine S4 over other selective androgen receptor modulators. Despite these concerns, its rapid results and effectiveness in a dose-dependent manner continue to make it a popular choice among those seeking to enhance their muscle and bone tissues.
S-4 Andarine for Sale
While looking for S-4 Andarine, it is highly recommended that you buy from a reputed source to avoid any discrepancies in clinical research and trials. Loti Labs sells the best quality S-4 Andarine online that goes through a rigorous quality-check process before reaching you.